Why Deferoxamine Therapy Predisposes to Yersinia sepsis
نویسندگان
چکیده
منابع مشابه
Transfusion-transmitted Yersinia enterocolitica sepsis.
Bacterial sepsis has become the most frequent infectious complication of transfusion. Although Yersinia enterocolitica is a common enteropathogen usually causing relatively mild disease, it is nevertheless a prominent cause of life-threatening post-transfusion infection. To gain a better understanding of the clinical presentation and prognosis of this rare occurrence, we performed a systematic ...
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M ucormycosis is an uncommon acute and often fatal opportunistic fungal infection that usually occurs in patients with poorly controlled diabetes mellitus, acute leukemias, or other immunosuppressive conditions [1,2]. A new association, that of mucormycosis occurring in patients receiving deferoxamine therapy for iron or aluminum excess, has been reported with increasing frequency since 1986 [3...
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To examine the potential clinical usefulness of the hexadentate phenolic aminocarboxylate iron chelator N, N-bis(2-hydroxybenzyl)ethylenediamine-N,N-diacetic acid (HBED) for the chronic treatment of transfusional iron overload, we compared the iron excretion induced by subcutaneous (SC) injection of HBED and deferoxamine (DFO), the reference chelator, in rodents and primates. In the non-iron-ov...
متن کاملSevere Yersinia enterocolitica sepsis after blood transfusion.
A 23-year-old male received multiple blood transfusions following complicated thoracic surgery. He developed progressive haemorrhagic shock and multiple organ dysfunction syndrome. Blood cultures grew Yersinia enterocolitica. The patient was proven negative for Yersinia enterocolitica; however, one of the donors was found to be positive. Although strict selection of blood transfusion donors is ...
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Yersinia enterocolitica is the cause of gastrointestinal infection in the overwhelming majority of recognized cases, although extraintestinal sites are occasionally involved. We report a case of Y. enterocolitica septicemia and empyema complicated by the adult respiratory distress syndrome. The organism was also recovered from the patient's feces by alkaline enrichment and persisted through at ...
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ژورنال
عنوان ژورنال: Acta Haematologica
سال: 1987
ISSN: 0001-5792,1421-9662
DOI: 10.1159/000205991